Vivekanand Bhardwaj

Education

• M.S. (Pharm.) from National Institute of Pharmaceutical Education & Research (July 2002-December 2003, Specialization in pharmaceutics).

• GATE 2002:   96.38 percentile score

• B. Pharm. from Delhi Institute of Pharmaceutical Education and Research (DIPSAR, formerly known as College of Pharmacy), University of Delhi (70.6 %), 1999-2002

• D. Pharm. from Delhi Institute of Pharmaceutical Education and Research (DIPSAR, formerly known as College of Pharmacy), University of Delhi, 1997-1999

Awards/Scholarships/Other Recognition

• NIPER Research Fellowship (July 2002-Dec 2003), (July 2004-Feb 2006), (March 2007-08)

• Marie-Curie EST Fellowship (Feb 2006-07)

Patents

• M. N. V. Ravi Kumar, D. D. Ankola, V. Bhoomi, V. Bhardwaj and P. Ramarao, Nanoparticulate formulation of Coenzyme Q10. Indian Patent Application 18/Del/2006

• M. N. V. Ravi Kumar, N. Kashyap, V. Bhoomi, V. Bhardwaj, P. Ramarao and N. Kumar, Design of glucose sensitive in situ gelling system based on chitosan for pulsatile delivery of insulin. Indian Patent Application 36/del/2006

• M. N. V. Ravi Kumar, D. Venkat Ratnam, Kiran Sonaje, V. Bhoomi, V. Bhardwaj and P. Ramarao, Nano-co-encapsulated antioxidant particles (NanoCAPs). Indian Patent Application 1691/del/2006

• M. N. V. Ravi Kumar, J. L. Italia, D. Bhatt , V. Bhardwaj and K. B. Tikoo, Nanoparticles containing cyclosporine. Indian Patent Application 1690/del/2006

• M. N. V. Ravi Kumar, V. Bhardwaj and D. D. Ankola, Polymeric nanoparticles of paclitaxel for treatment of cancers. Indian Patent Application 2636/del/2006

Publications

Articles in Peer Reviewed Journals

• Panchagnula, R. and V. Bhardwaj. "Effect of Amorphous Content on Dissolution Characteristics of Rifampicin." Drug Development and Industrial Pharmacy 34 (2008): 642 - 649

• D. Venkat Ratnam, G. Chandraiah, K. Sonaje, B. Viswanad, V. Bhardwaj, P. Ramarao, and M. N. V. Ravi kumar, A Potential Therapeutic Strategy for Diabetes and Its Complications in the Form of Co-Encapsulated Antioxidant Nanoparticles (NanoCAPs) of Ellagic Acid and Coenzyme Q10: Preparation and Evaluation in Streptozotocin Induced Diabetic Rats Journal of Biomedical Nanotechnology 4 (2008) 33-43

• D. Sahana, G. Mittal, V. Bhardwaj and M. N. V. Ravi Kumar, PLGA Nanoparticles for Oral Administration of hydrophobic drugs: Influence of organic solvent on nanoparticle formation and release behavior in vitro and in vivo using estradiol as a model drug, Journal of Pharmaceutical Sciences 97 (2008) 1530-1542

• J.L. Italia, D.K. Bhatt, V. Bhardwaj, K. Tikoo and M.N.V. Ravi Kumar. PLGA nanoparticles for oral delivery of cyclosporine: Nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral Journal of Controlled Release 119 (2007) 197-206

• K. Sonaje, J. Italia, G. Sharma, V. Bhardwaj, K. Tikoo and M. N. V. Ravi Kumar, Development of biodegradable nanoparticles for oral delivery of ellagic acid and evaluation of their antioxidant efficacy against cyclosporine A-induced nephrotoxicity in rats, Pharmaceutical Research 24 (2007) 899-908

• D. D. Ankola, B. Viswanad, V. Bhardwaj, P. Ramarao, MNV RaviKumar, Development of potent oral nanoparticulate formulation of coenzyme Q10 for treatment of hypertension: Can the simple nutritional supplements be used as first line therapeutic agents for prophylaxis/therapy? European Journal of Pharmaceutics & Biopharmaceutics 67 (2007) 361-369.

• G. Mittal, D. K. Sahana, V. Bhardwaj and M. N. V. Ravi Kumar, Estradiol Loaded PLGA Nanoparticles for Oral Administration: Effect of Polymer Molecular Weight and Copolymer Composition on Release Behavior In Vitro and In Vivo. Journal of Controlled Release 119 (2007) 77-85.

• N. Kashyap, B. Viswanad, G. Sharma, V. Bhardwaj, P. Rama Rao and M. N. V. Ravi Kumar Design and evaluation of biodegradable, biosensitive in situ gelling system for pulsatile delivery of insulin, Biomaterials 28 (2007) 2051-2060

• J. Italia, V. Bhardwaj and M. N. V. Ravi Kumar, Disease, Destination, Dose and Delivery Aspects of Ciclosporin: The State of the Art, Drug Discovery Today, 11 (2006) 846-854.

• D. Venkat Ratnam, D. D. Ankola, V. Bhardwaj, D. K. Sahana, M. N. V. Ravi Kumar, The role of Antioxidants in Prophylaxis And Therapy: A Pharmaceutical Perspective, Journal of Controlled Release 113 (2006) 189-207.

• D. Venkat Ratnam, V. Bhardwaj, M.N.V. Ravi Kumar, Simultaneous analysis of ellagic acid and coenzyme Q10 by derivative spectroscopy and HPLC, Talanta 70 (2006) 387-391.

• S. Hariharan, V. Bhardwaj, I. Bala, J. Sitterberg, U. Bakowsky and M. N. V. Ravi Kumar, Design of estradiol loaded PLGA nanoparticulate formulations: A Potential oral delivery system for hormone therapy., Pharm.Res., 23 (2006) 184-196.

• I. Bala, V. Bhardwaj, S. Hariharan, S. Karade, N. Roy, and M. N. V. Ravi Kumar, Sustained release nanoparticulate formulation containing antioxidant-ellagic acid as potential prophylaxis system for oral administration, Journal of Drug Targeting 14 (2006) 27-34.

• I. Bala, V. Bhardwaj, S. Hariharan and M. N. V. Ravi Kumar, Analytical Methods for assay of Ellagic Acid and its solubility studies, J. Pharm. Biomed. Anal., 40 (2006) 206-210.

• I. Bala, V. Bhardwaj, S. Hariharan, J. Sitterberg, U. Bakowsky and M. N. V. Ravi Kumar, Design of Biodegradable Nanoparticles: A Novel Approach to Encapsulate Poorly Soluble Phytochemical Ellagic acid, Nanotechnology 16 (2005) 2819-2822.

• V. Bhardwaj, S. Hariharan, I. Bala, A. Lamprecht, N. Kumar, R. Panchagnula, M. N. V. Ravi Kumar, Pharmaceutical aspects of polymeric nanoparticles for oral delivery, Journal of Biomedical Nanotechnology. 1 (2005) 235-258.

Book Chapters

• V. Bhardwaj, and M. N. V. Ravi Kumar, Polymeric nanoparticles for oral drug delivery; In: Nanoparticle Technologies for Drug Delivery. Ram B. Gupta and Uday B. Kompella (Eds.). Marcel Dekker, Inc. New York

• V. Bhardwaj, and M. N. V. Ravi Kumar, Polymeric nanoparticles for oral drug delivery; In: Nanoparticles for Pharmaceutical Applications. A. J. Domb, Y. Tabata, and M. N. V. Ravi Kumar (Eds.). American Scientific Publishers, USA

• N. Nafee, V. Bhardwaj and M. Schneider, Transport across biological barriers, In: Nanotherapeutics — Drug Delivery Concepts in Nanoscience. Alf Lamprecht (Ed) ---- World Scientific Publishing Company, USA

Conference Presentations

• V. Bhardwaj, D.D. Ankola, and M. N. V. Ravi Kumar, PLGA nanoparticles of Paclitaxel (Taxol) for the treatment of solid tumors, Proceedings of 35^th Controlled Release Society Annual Meeting, July 12-16, New York USA.

• V. Bhardwaj, M. Schneider, U. Schaefer, C-M. Lehr, Toxicity and  Pgp efflux studies with cationic quaternary ammonium salt didodecyldimethyl ammonium bromide (DMAB) and its application in fabricating PLGA nanoparticles, Pharmaceutical Sciences World Congress, April 22-25 2007, Amsterdam, Netherlands

• D.D. Ankola, V. Boomi, V. Bhardwaj, P. Ramarao and M.N.V. Ravi Kumar, Potent oral nanoparticulate formulation of E115 for treatment of hypertension, International Nanomedicine and Drug Delivery Symposium, October 8-10, 2006, Omaha, USA.

• D. Venkat Ratnam, G.Chandraiah, V. Bhoomi, V. Bhardwaj, P. Rama Rao, M. N. V. Ravi Kumar, NanoCAPs: A Novel Antioxidants Delivery Approach for Diabetic Complications, International Nanomedicine and Drug Delivery Symposium, October 8-10, 2006, Omaha, USA.

• J. L. Italia, D. K. Bhatt, V. Bhardwaj, K. B. Tikoo and M.N.V. Ravi Kumar, Design of Cyclosporine Loaded Biodegradable Nanoparticles for Oral Delivery: Improved Intestinal uptake and Reduced Nephrotoxicity in Rats, Proceedings of 33rd Controlled Release Society Annual Meeting, July 22-26, 2006, Vienna, Austria

• S. Hariharan, I. Bala, V. Bhardwaj and M.N.V. Ravi Kumar, Preparation and optimization of Estradiol loaded nanoparticles intended for oral delivery; Proceedings of 32^nd Controlled Release Society Meeting, Miami, 18-22^nd  June’2005.

• V. Bhardwaj, D. D. Ankola, M. N. V. Ravi Kumar. Potent Route Independent Paclitaxel Formulation: Implications of Nanotechnology for Safe and Effective Chemotherapy. Nominated for BioAsia Innovation Award-2007 for Young Scientists.

• N. Kashyap, V. Bhoomi, G. Sharma, V. Bhardwaj, M. N. V. Ravi Kumar. Design of glucose sensitive in situ gelling system based on chitosan for pulsatile delivery of insulin. Nominated for BioAsia Innovation Award-2007 for Young Scientists

Professional Activities

Seminars Delivered

• Potential of Biodegradable Nanoparticles in Oral drug delivery, Advances in Medical Diagnostics, University of Strathclyde, Glasgow, 11^th September 2008

Conferences and Workshops Attended

• 40^th Annual Conference of Indian Pharmacological Society, NIPER, Mohali, INDIA, 1^st-3^rd November, 2007

• Pharmaceutical World Science Congress, April 2007 at Amsterdam, Netherlands

• Pre satellite meeting of Pharmaceutical World Science Congress, April 2007 at Amsterdam, Netherlands

• Galenos Intensive course, Jan-Feb 2007, Hradec Kralove, Czech Republic

• Controlled Release Society meeting in June 2006, Vienna, Austria

• Galenos thematic workshop, 2006 in University of Cagliari, Sardinia, Italy

• Cell Course, March 2006 at University of Saarland,  Saarbruecken, Germany

Areas of interest

• Nanotechnology aided drug delivery

• Novel Drug Delivery Systems

• Solid State Pharmaceutics

• Formulation Development and Preformulation

• Pharmacokinetics and Biopharmaceutics

• IPR & Regulatory Affairs

• Web development

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